Calculate the molar mass of Arsenic Trioxide in grams per mole or search for a chemical formula or substance.
among patients with chemotherapy treatment for advanced colorectal cancer. Molin Y., P Frisk, N-G Ilbäck. Sequential effects of daily arsenic trioxide treatment
It is used: In adults with newly diagnosed APL that is low risk. It is also used to treat APL in certain people who have not been helped by other types of chemotherapy or whose condition has improved but then worsened following treatment with a retinoid and other types of chemotherapy treatment(s). Arsenic trioxide is in a class of medications called anti-neoplastics. 2021-02-09 2002-07-15 chemotherapy with ATRA plus arsenic trioxide in patients with APL classified as low-to-intermediate risk (white-cell count, ≤10×109 per liter). Patients were randomly assigned to receive either ATRA plus arsenic trioxide for induction and consolidation therapy or standard ATRA–idarubicin induction therapy ATRA (Tretinoin) + Arsenic Trioxide (Trisenox®) is a Chemotherapy Regimen for Acute Promyelocytic Leukemia (APL) How does ATRA + Arsenic Trioxide work? At diagnosis, APL cells are "trapped" in an immature phase of maturation, do not function normally, and can suppress the … The therapeutic advantage of the association of ATRA + Arsenic Trioxide is more favorable and manageable as compared to ATRA + chemotherapy. Nevertheless, at present, there is not enough information on the incidence of long-term side effects.
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During the last decade, the efficacy of arsenic trioxide in both newly diagnosed and relapsed patients with APL3 has been estab-lished. Arsenic trioxide can be used as a single agent and induces complete remissions with only minimal myelosuppression (1). Inves-tigators in China introduced arsenic trioxide, alone and in combination Arsenic trioxide is readily absorbed by the digestive system: toxic effects are also well known upon inhalation or upon skin contact. Elimination is rapid at first (half-life of 1–2 days), by methylation to monomethylarsonic acid and dimethylarsonic acid, and excretion in the urine, but a certain amount (30–40% in the case of repeated exposure) is incorporated into the bones, muscles, skin Arsenic trioxide Accord is used to treat adults (aged 18 years or over) with acute promyelocytic leukaemia (APL), a rare form of leukaemia (cancer of the white blood cells) caused by a genetic ‘translocation’ (when there is a swap of genes between two chromosomes). INTRODUCTION Small cell lung cancer (SCLC) carries high mortality despite standard chemotherapy. Arsenic trioxide (ATO) has demonstrated clinical efficacy in leukemia and in vitro activity in various solid tumors.
Arsenic trioxide is in a class of medications called anti-neoplastics. 2021-02-09 2002-07-15 chemotherapy with ATRA plus arsenic trioxide in patients with APL classified as low-to-intermediate risk (white-cell count, ≤10×109 per liter). Patients were randomly assigned to receive either ATRA plus arsenic trioxide for induction and consolidation therapy or standard ATRA–idarubicin induction therapy ATRA (Tretinoin) + Arsenic Trioxide (Trisenox®) is a Chemotherapy Regimen for Acute Promyelocytic Leukemia (APL) How does ATRA + Arsenic Trioxide work?
arrowhead/MS arrowroot/MS arroyo/SM arsenal/SM arsenate/M arsenic/MS chemotherapy/SM chemurgy/SM chenille/MS cherish/DRSG cherisher/M trio/MS triode/SM trioxide/M trip/MYS tripartite/N tripartition/M tripe/SM triphenylarsine
Arsenic trioxide is used alone or in combination for the treatment of acute promyelocytic leukemia. It is reserved for patients that do not respond to (or relapse with) first line therapy with retinoid and anthracycline chemotherapy [21].
Arsenic trioxide (Trisenox, ATO) Arsenic trioxide is a chemotherapy drug and is also called Trisenox or ATO. It is a treatment for a type of acute myeloid leukaemia called acute promyelocytic leukaemia (APL).
Induction of remission and consolidation in adult patients with. • newly diagnosed low-to-intermediate risk acute This is not surprising, since the combination of ATRA plus arsenic trioxide without chemotherapy has a 98% 5-year event-free survival in low- risk patients and Dec 5, 2016 SAN DIEGO – All-trans retinoic acid (ATRA) plus arsenic trioxide with or without chemotherapy induces high remission rates among patients Arsenic Trioxide (Trisenox) is given intravenously (IV) to treat cancer. Find side effects, allergic reactions, and food and drug interactions. Mar 1, 2021 Arsenic trioxide injection is used together with another medicine (eg, tretinoin) to treat newly-diagnosed low-risk acute promyelocytic leukemia Dec 31, 2000 The injectable form of arsenic trioxide (Trisenox) was recently md, investigator in the Developmental Chemotherapy Service atMemorial Use of all-trans retinoic acid plus arsenic trioxide as an alternative to chemotherapy in untreated acute promyelocytic leukemia. Blood 2006;107:3469- 3473. 11.
It is used: In adults with newly diagnosed APL that is low risk. It is also used to treat APL in certain people who have not been helped by other types of chemotherapy or whose condition has improved but then worsened following treatment with a retinoid and other types of chemotherapy treatment(s). Arsenic trioxide is in a class of medications called anti-neoplastics. 2021-02-09
2002-07-15
chemotherapy with ATRA plus arsenic trioxide in patients with APL classified as low-to-intermediate risk (white-cell count, ≤10×109 per liter).
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Arsenic trioxide is in a class of medications called anti-neoplastics. As all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) are widely accepted in treating acute promyelocytic leukemia (APL), deescalating toxicity becomes a research hotspot. Here, we evaluated whether chemotherapy could be replaced or reduced by ATO in APL patients at different risks. Experimental group receive arsenic trioxide combined with induction chemotherapy while control group receive conventional induction chemotherapy alone. The 3 year overall survival rate (OS) and progression free survival (PFS), as well as incidence of adverse events, will be compared between two groups.
Arsenic trioxide is an established cardiac toxin.
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Sep 9, 2011 ATO is either included into induction therapy with the aim to minimize or eliminate chemotherapy, or it is incorporated as an additive into
Of the 67 patients with relapsed acute promyelocytic leukaemia (APL) treated with arsenic trioxide (ATO)‐based re‐induction therapy, 63 (94%) achieved molecular remission; 35 (55·6%) underwent autologous stem cell transplantation (Auto‐SCT) and 28 (44·4%) were consolidated with ATO‐based maintenance chemotherapy. 2017-09-06 · Arsenic is stored mainly in liver, kidney, heart, lung, hair and nails. In vitro enzymatic studies with human liver microsomes revealed that arsenic trioxide has no inhibitory activity on substrates of the major cytochrome P450 enzymes such as 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, 3A4/5, 4A9/11. Excretion Purpose The initial results of the APL0406 trial showed that the combination of all-trans-retinoic acid (ATRA) and arsenic trioxide (ATO) is at least not inferior to standard ATRA and chemotherapy (CHT) in first-line therapy of low- or intermediate-risk acute promyelocytic leukemia (APL).
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Introduction: Arsenic trioxide is effective and approved for treatment of relapsed or refractory acute promyelocytic leukemia (APL) cases resistant to all-trans retinoic acid (ATRA), but its effect on new cases of APL is not clear. Materials and methods: We studied 111 patients with APL.
chemotherapy, 43% for chemotherapy and BMT and 82% for chemotherapy plus arsenic trioxide (p = 0.0004). In a randomized controlled trial of arsenic trioxide monotherapy vs. arsenic trioxide plus ATRA therapy in 20 patients with relapsed APL, Raffoux and colleagues6 demonstrated a CR2 rate of 80% after one ATRA (Tretinoin) + Arsenic Trioxide (Trisenox®) is a Chemotherapy Regimen for Acute Promyelocytic Leukemia (APL) How does ATRA + Arsenic Trioxide work? At diagnosis, APL cells are "trapped" in an immature phase of maturation, do not function normally, and can suppress the growth of good cells in the bone marrow. Arsenic trioxide, a cancer chemo drug hampers fibrotic liver regeneration by interrupting oxidative stress rekindling and stellate cell rejuvenation J Cell Physiol .
31 mars 2021 — Koncentrat till infusionsvätska, 1 mg/ml, Arsenic Trioxide Accord 2569, Dutasterid, Kapsel, 0,5 mg, Dutasteride Chemo Ibérica, 0,5 mg
Arsenic trioxide is used to treat a cancer of the blood and bone marrow called acute promyelocytic (pro-MYE-loe-SIT-ik) leukemia, or APL. Arsenic trioxide is sometimes given in combination with another medicine called tretinoin. Arsenic trioxide may also be used for other purposes not listed in this medication guide.
some types of acute myeloid leukemia.